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Safe RL, generative personalization, contrastive physiological modeling, scientific computing, uncertainty quantification, wearable health algorithms, selected publications, and deployed product work.
Basics
| Name | Zexin Liu |
| Label | Medical AI and Wearable Health Algorithm Researcher |
| liu.zexin9518@gmail.com | |
| Url | https://zexinliu.github.io |
| Summary | Advanced algorithm engineer at HONOR with a Ph.D. in Mathematics from the University of Utah. I combine scientific computing, uncertainty quantification, physiological signal modeling, safe reinforcement learning, generative modeling, and contrastive representation learning to build deployable medical and wearable health algorithms. |
Work
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Advanced Algorithm Engineer
HONOR
Research and development of medical and health-related algorithms for wearable devices, with emphasis on physiological signal modeling, representation learning, calibration, and product-level robustness.
- Led commercialization of 24-hour continuous non-invasive blood pressure monitoring for the HONOR Watch 5 Pro.
- Led commercialization of sudden cardiac arrest screening based on heart-rate deceleration capacity for the HONOR Watch 5 Ultra.
- Worked on physiological signal modeling, multimodal representation learning, calibration, domain adaptation, and health-feature algorithm pipelines.
- Developed applied project tracks in safe RL for physiological control, conditional generative personalization for cuffless BP, ECG/PPG contrastive learning for deceleration-capacity screening, and uncertainty-aware biomedical simulation.
Education
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Beijing, China
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Salt Lake City, Utah, United States
Ph.D. in Mathematics
University of Utah
Mathematics; scientific computing and uncertainty quantification
- Advisor: Professor Akil Narayan
- Orthogonal polynomial recurrence algorithms for nonclassical measures
- Multivariate Stieltjes algorithms and recurrence matrices
- Polynomial chaos expansion and noninvasive uncertainty quantification
- Open-source UQ software for computational biomedical simulations
Awards
- 2025.08.01
Beijing High-Level Overseas Talent Funding Program
Beijing
Recognized by the Beijing High-Level Overseas Talent Funding Program.
- 2025.01.08
Publications
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2024.01.01 Influence of material parameter variability on the predicted coronary artery biomechanical environment via uncertainty quantification
Biomechanics and Modeling in Mechanobiology
Applied uncertainty quantification to study how vascular material parameter variability propagates to predicted coronary artery biomechanics.
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2023.01.01 UncertainSCI: Uncertainty quantification for computational models in biomedicine and bioengineering
Computers in Biology and Medicine
Presented UncertainSCI as a lightweight tool for polynomial-chaos-based uncertainty quantification in biomedical and bioengineering simulations.
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2023.01.01 UncertainSCI: A Python Package for Noninvasive Parametric Uncertainty Quantification of Simulation Pipelines
The Journal of Open Source Software
Described the UncertainSCI Python package for noninvasive parametric uncertainty quantification of simulation pipelines.
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2023.01.01 A Stieltjes Algorithm for Generating Multivariate Orthogonal Polynomials
SIAM Journal on Scientific Computing
Introduced a Multivariate Stieltjes algorithm for computing recurrence matrices and stable multivariate orthogonal polynomial bases.
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2021.01.01 On the Computation of Recurrence Coefficients for Univariate Orthogonal Polynomials
Journal of Scientific Computing
Developed and evaluated algorithms for computing recurrence coefficients for univariate orthogonal polynomial families.
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2020.01.01 Using UncertainSCI to Quantify Uncertainty in Cardiac Simulations
Computing in Cardiology
Applied UncertainSCI to quantify how heart position and tissue conductivity uncertainty propagate to cardiac simulation outputs.
Skills
| Scientific Computing and Uncertainty Quantification | |
| Orthogonal polynomials | |
| Polynomial chaos | |
| Gaussian quadrature | |
| Biomedical simulations | |
| UncertainSCI |
| Medical AI and Wearable Health Algorithms | |
| Physiological signals | |
| Photoplethysmography | |
| Electrocardiogram | |
| Blood pressure prediction | |
| Deceleration capacity | |
| Calibration | |
| Domain adaptation |
| Generative Modeling and Representation Learning | |
| Contrastive learning | |
| Flow matching | |
| Diffusion models | |
| Multimodal learning | |
| Signal denoising | |
| Representation learning |
| Safe Reinforcement Learning and Physiological Control | |
| Safe RL | |
| Constrained MDP | |
| Action shielding | |
| Physiological control | |
| Simulation-based evaluation | |
| Treadmill control |
| Medical Large Models | |
| Fine-tuning | |
| Medical-domain adaptation | |
| Healthcare evaluation | |
| Knowledge-grounded modeling | |
| Healthcare workflow modeling |
| AI Systems | |
| Distributed training | |
| Large language model inference | |
| Paged KV cache | |
| Tensor parallelism | |
| vLLM |
Languages
| Chinese | |
| Native speaker |
| English | |
| Professional working proficiency |
Interests
| Research and Engineering Interests | |||||||||
| Medical AI | |||||||||
| Wearable health | |||||||||
| Scientific computing | |||||||||
| Uncertainty quantification | |||||||||
| Safe reinforcement learning | |||||||||
| Generative personalization | |||||||||
| Multimodal contrastive learning | |||||||||
| Large-model systems | |||||||||
Projects
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24H Cuffless Blood Pressure Monitoring
Wearable PPG blood pressure monitoring project with personalization, calibration, generative modeling, and product-level robustness.
- PPG blood pressure regression
- Personalized calibration
- Generative personalization
- Calibration-aware modeling
- Product deployment
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Deceleration Capacity Screening from Wearable Signals
Wearable heart-risk screening project based on deceleration capacity theory, ECG/PPG representation learning, and long-horizon physiological aggregation.
- ECG/PPG representation learning
- Deceleration capacity
- Signal-quality-aware modeling
- 24-hour aggregation
- Wearable health-study deployment
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SafeRunRL: Safe Reinforcement Learning for Adaptive Treadmill Control
Simulation-based safe RL prototype for adaptive treadmill speed and incline control from wearable physiological signals.
- Wearable state estimation
- Personalized cardiovascular simulator
- Constrained MDP
- Action shield
- Stress-test evaluation
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Orthogonal Polynomials and Biomedical Uncertainty Quantification
Ph.D. research on recurrence algorithms, polynomial chaos expansion, UncertainSCI, and reliable biomedical simulation uncertainty quantification.
- Univariate recurrence coefficients
- Multivariate Stieltjes algorithm
- Polynomial chaos
- UncertainSCI